I discovered this on an anthropology blog, and the link to the original release is here.
In summary, men with the I-haplogroup have a higher risk of CHD. These are people who most likely migrated to Europe about 25,000 years ago, long before the first farmers. Chances are they are also less adapted to Neolithic foods.
And there are resons to think that mtDNA also plays a role in adaptation to Neolithic food, as well as glacial cold. Perhaps those of us who have genes of ancestral H-G Europeans fare better on high fat than the later immigrant farmers?
It would be interesting to compare susceptability to chronic diseases in U (first wave of Paleo Europeans), H (second wave) and later Neolitic farmers (J, T).